Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.
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چکیده
منابع مشابه
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
Interleukin 7 (IL-7) stimulates the proliferation of B cell progenitors, thymocytes, and mature T cells through an interaction with a high affinity receptor (IL-7R) belonging to the hematopoietin receptor superfamily. We have further addressed the role of IL-7 and its receptor during B and T cell development by generating mice genetically deficient in IL-7R. Mutant mice display a profound reduc...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1994
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.180.5.1955